Author

Min Kyung Lee

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Review Open access Oct 2026

Evaluation of anti-nuclear antibody patterns and their associations with autoimmune disease biomarkers

Anti-nuclear antibody (ANA) testing is widely used in the evaluation of systemic autoimmune rheumatic diseases (SARD). We evaluated ANA testing performed at Labcorp between 2015 and 2024 and examined serological associations between ANA titers and HEp-2 indirect immunofluorescence assay (IFA) patterns and commonly...

Min Kyung Lee, V. Ricchiuti · Frontiers in Immunology · 0 citations

Oct 2026

B-200 CORRELATION OF ANTI-DFS70 AUTOANTIBODY WITH HEP-20-10 CELL IMMUNOFLUORESCENCE ASSAY FOR NUCLEAR DENSE FINE SPECKLED PATTERN AC-2

Over the past two decades, the identification and characterization of the dense fine speckled (DFS; ICAP AC-2) nuclear pattern in antinuclear antibody (ANA) testing-observed using HEp-2 or HEp-20-10 cells in indirect immunofluorescence assays (IFA)-has significantly influenced the landscape of ANA diagnostics. Th...

V. Ricchiuti, Breann Losiewicz, Ilana Heckler et al. · Clinical Chemistry · 0 citations