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Open access Oct 2026

Performance Characteristics for Flow Cytometric Enumeration of Peripheral Blood Lymphocyte Subsets under Harmonized Laboratory Conditions: A Multicenter Study.

BACKGROUND Flow cytometric enumeration of peripheral blood lymphocyte subsets (EPBLS) is essential for disease management, yet standardized validation criteria are lacking. We defined key performance characteristics under harmonized conditions to support criteria development. METHODS 205 whole blood samples and 54 qu...

Lin Xiao, Yuan Wang, Yi Li et al. · 0 citations
Sep 2026

Machine learning-based discrimination of metabolic dysfunction-associated steatotic liver disease: implications of tryptophan metabolites as potential biomarkers.

OBJECTIVES Early screening of individuals at high risk of metabolic dysfunction-associated steatotic liver disease (MASLD) facilitates timely intervention and may reduce the risk of progression to cirrhosis. This study aimed to develop a reliable and clinically practical model for MASLD discrimination. METHODS A tota...

Zhen-Ni Liu, Si-Yu Li, Yan Tan et al. · 0 citations

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