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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Min Chen

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3 papers indexed here

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Open access Aug 2026

PCIM-DTA: Pairwise Conditional Interaction Modeling for Drug-Target Affinity Prediction under Cold-Start Scenarios.

MOTIVATION Cold-start drug-target affinity prediction remains challenging because static interaction mechanisms cannot adapt to individual drug-target pairs. RESULTS We propose PCIM-DTA, which constructs pair-level interaction representations and derives a pair-specific condition vector from global drug and target fe...

Zi-You Zhou, Min Chen, Wen-Jia Zhou et al. · 3 citations
Open access Sep 2026

Spatial cell-cell communication inference based on cell-spot-ligand-receptor heterogeneous graphs.

Cell-cell communication is essential for tissue homeostasis and disease-associated microenvironment remodeling. Spatial transcriptomics enables the study of communication events in situ, but single-cell-resolution inference from spot-based data remains challenging because of uncertain cell-to-spot mapping, limited use...

Xiong Li, Dong-Ding Wu, Yue-Jin Zhang et al. · 0 citations
Sep 2026

Similarity-Adaptive interaction routing for Drug-Target affinity prediction.

SIGMA-DTA, a similarity-guided adaptive interaction modeling framework for DTA prediction, introduces a similarity-driven routing mechanism that adjusts information propagation under different similarity levels and can model complex drug-target relationships more effectively.

Zi-You Zhou, Min Chen, Wen-Jia Zhou et al. · 1 citation

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