Target-responsive "signal-down" electrochemical biosensor based on an anti-biofouling hydrogel for glutathione detection.
Glutathione (GSH), a ubiquitous biothiol, is critical in physiological processes, and abnormal fluctuations in its level are intimately associated with various diseases. However, real-time in vivo monitoring of GSH within tissues, such as the tumor microenvironment (TME), is fundamentally hindered by severely electrode...