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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Min-Ah Suh

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Open access Sep 2026

Targeting glial PD-1/PD-L1 restores microglial homeostasis and reduces neuronal hyperactivity in an Alzheimer’s disease model

Alzheimer’s disease (AD) involves complex neuroimmune dysregulation, and the role of immune checkpoint pathways in regulating neuro–glial interactions and intrinsic glial homeostasis remains unclear. In AD, glial expression of programmed cell death protein 1 (PD-1) and its ligand (PD-L1) is elevated in mouse models and...

Taeyoung Park, Leechung Chang, Seung Won Chung et al. · 0 citations
Open access Jul 2026

Active pH Modulation by Proton Channel‐Peptide Nucleic Acid Complex for Effective siRNA Endosomal Escape

The results indicate that the CPR complex interrupts the endosomal pathway, effectively reducing the colocalization of delivered siRNA with lysosomes and enhancing gene regulation efficiency, suggesting that the CPR nanocarrier design could serve as a versatile platform for targeted RNA delivery.

Seongmin Ga, Nam Hyeong Kim, Si Yeon Ryu et al. · 0 citations

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