Single-molecule spectroscopy is emerging as a powerful approach for elucidating the molecular structure and dynamics of biomolecular condensates. Unlike ensemble methods, it can resolve heterogeneous conformations, dynamics, interactions, concentrations, and transport properties across a broad range of length- and time...
Benjamin Schuler, Aritra Chowdhury, Miloš T. Ivanović et al.· Current Opinion in Structura...· 0 citations
All-atom simulations with explicit solvent can provide a detailed and accurate description of dynamics and mechanisms in biomolecular systems, including intrinsically disordered proteins (IDPs) and their condensates. However, interactions involving charged residues and ions remain a persistent source of systematic erro...
Miloš T. Ivanović, Valentin von Roten, Benjamin Schuler et al.· bioRxiv· 0 citations
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