A dual functional hybrid lipid-polymeric nanoparticle co-loaded coenzyme Q10 and siRNA TNFα for anti-inflammatory skin therapy.
Inflammatory skin diseases, such as psoriasis, lead to significant humanistic and economic burdens, mainly psychosocial impacts due to the relapsing papulosquamous characteristic of the disease. Due to the extensive skin lesions, topical therapies remain the main form of treatment. However, their effectiveness is limit...