Miguel Xavier

Microsatellite instability detection in extracellular vesicles of short-chain fatty acids-treated colorectal cancer cells

Late-stage diagnosis renders colorectal cancer (CRC) a major health challenge, mostly due to the lack of reliable non-invasive biomarkers. Although microsatellite instability (MSI) is a promising genetic biomarker guiding immunotherapy selection, its detection still relies on invasive sampling. Here, we explored whet...