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Author

Miguel Castelo-Branco

3 papers indexed here

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Open access Aug 2026

Effects of lovastatin on cortical excitability, E/I balance, and antioxidant markers in a case series of patients with drug-resistant epilepsy: a proof-of-concept study.

BACKGROUND Drug-resistant epilepsy (DRE) remains a major clinical challenge, with neuroinflammation and excitatory/inhibitory (E/I) imbalance being implicated in its pathophysiology. This proof-of-concept case series aimed to investigate the neurochemical and neurophysiological effects of a short course of lovastatin i...

S. I. Abuhaiba, I. Duarte, F. Sales et al. · 0 citations
Open access Oct 2026

Inhibitory control and error processing in Obsessive-Compulsive Disorder: A mega-analysis of task-based fMRI data by the ENIGMA-OCD consortium.

OBJECTIVE Obsessive-compulsive disorder (OCD) is a chronic condition in which impaired inhibitory control and excessive error monitoring may contribute to maintenance of obsessions and compulsions. This mega-analysis investigates neural activation during response inhibition and error processing using adult (OCD=563; co...

N. Džinalija, O. A. van den Heuvel, H. B. Simpson et al. · 0 citations
Open access Aug 2026

A negative association between functional profiles in multiple cognitive domains and cortical thickness in Down Syndrome.

BACKGROUND People with Down syndrome (DS) have intellectual disability and a distinct neuroanatomy due to genetic-induced atypical neurodevelopment. Although a few previous studies have shown increased cortical thickness (CT) in this syndrome, their functional impact remains to be investigated. Here we addressed this q...

L. Jorge, Joana Oliveira, N. Canário et al. · 0 citations

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