Miguel A. S. Martín-Aragón Baudel

Blood Pressure Tunes the Functional Coupling of Cerebrovascular CaV1.2 Channels.

BACKGROUND The myogenic response is the key autoregulatory mechanism that sets cerebral blood flow, and its mechanistic foundation is intimately tied to depolarization and the voltage gating of L-type Ca2+ channels (CaV1.2). Although critical, this study argues for an additional mechanism. We hypothesize that increased...