Open access
Jul 2026
Polyvinylpyrrolidone enhances AAV transduction in vitro and shows preliminary utility for subretinal delivery
Findings support further evaluation of PVP40 for local subretinal AAV delivery and support unmodified linear polyvinylpyrrolidone (PVP), a pharmaceutical excipient, can improve AAV formulation without chemical modification of the vector or polymer.
N. Gogoleva, T. Tran, Mayuko Oki et al.
· bioRxiv · 0 citations