Michelle D. Jung

The black fly salivary protein Simukunin inhibits complement activation through the lectin pathway protease MASP-2

Salivary secretions from blood-feeding arthropods are enriched with bioactive molecules that counteract host hemostatic and immune defenses, including blood coagulation, platelet aggregation, complement activation, and vasoconstriction. Although numerous salivary components have been identified and functionally charact...