Open access
Sep 2026
In utero barcoding of mouse mesoderm reveals the clonal architecture of organ mesenchyme
The mesoderm coordinates organogenesis and generates the cardiovascular, visceral and musculoskeletal systems, yet in mammals this germ layer is difficult to access, impeding its genetic manipulation and study. Here, we establish embryonic day (E) 7.5 exocoelomic cavity nano-injection as a scalable route for selective...
Jing-Yan He, J. Lorentz, A. Corbat et al.
· bioRxiv · 0 citations