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Author

Michael R. Green

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Oct 2026

Abstract C147: U54 Cancer Health Disparities Specialized Program of Research Excellence: The Lymphoma Outcomes SPORE

Diffuse large B-cell lymphoma (DLBCL), the most common hematologic cancer in the US, is characterized by marked molecular and clinical heterogeneity. African American (AA) and Hispanic patients experience inferior outcomes due to biologic factors that remain poorly understood, in addition to well-described socioecono...

J. Koff, Jonathon B. Cohen, Lee A. D. Cooper et al. · 0 citations
Open access Sep 2026

Structural and functional divergence of cancer hotspot mutations in CREBBP

The crystal structures of recurrent hotspot mutations in the CREBBP acetyltransferase are solved and it is shown that the arginine 1446 hotspot has a unique impact on substrate binding and acetyltransferase activity.

Wen-Chao Zhang, Hao-Peng Yang, Ariel E. Mechaly et al. · 0 citations
Open access Jul 2026

Clinical utility of real-time comprehensive molecular testing in large B-cell lymphoma.

The clinical utility and acceptable TAT of a comprehensive WES and RNA-seq assay for LBCL managed in routine clinical practice are demonstrated and support the real-world feasibility of using integrated WES and RNA-seq to define molecular subgroups, guide clinical decision-making at the time of a new line of therapy, a...

Dai Chihara, Kumudha Balakrishnan, G. Masand et al. · 0 citations

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