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Author

Michael R. Bene

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Open access Sep 2026

Sustained Activation of CaMKII Promotes Skeletal Muscle Contractile Dysfunction in Aging

It is shown that CaMKII protein abundance is increased in aged mouse skeletal muscle and that sustained CaMKII activation in young muscle is sufficient to impair contractile function before substantial atrophy develops and, with prolonged activation, to promote progressive muscle loss.

Michael R. Bene, Tae Chung, Elizabeth D. Luczak et al. · 0 citations

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