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Author

Meshael Alturki

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Review Open access Sep 2026

Peptide-Based Molecular Glues for Targeted Protein Degradation

This review examines the comparative advantages of peptide-based architectures, including reduced molecular weight, access to challenging interfaces, and expansion of the addressable E3 ligase repertoire, against persistent translational barriers in proteolytic stability, membrane permeability, immunogenicity, and manu...

Walaa S. Aburayan, Ibrahim A. Alradwan, Beshair A. Alsaffar et al. · 0 citations
Review Open access Aug 2026

From Delivery to Design: Site-Specific Genome Engineering for Next-Generation CAR T-Cell Therapy

Overall, site-specific integration provides a framework for linking CAR placement to therapeutic function, but no single locus or integration strategy is universally optimal and clinical evidence remains limited relative to the expanding preclinical landscape.

Hala Aldahshan, Abeer Al-Hubaysh, Dimah K. Alrabiah et al. · 0 citations

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