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Merav D. Shmueli

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#protein folding Open access Aug 2026

Human Hsp70 paralogs display selective J-domain interactions tuning proteostasis under stress

An evolved hierarchy of paralog-specific JDP couplings that dynamically rewires the Hsp70 network from active repair to protection during stress is revealed, revealing an evolved hierarchy of paralog-specific JDP couplings that dynamically rewires the Hsp70 network from active repair to protection during stress.

Roni Suhler, Lars J. W. van Beurden, Merav D. Shmueli et al. · 1 citation

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