Open access
Aug 2026
Loss of BCAP31 or POLR1E Accelerates Aging in C. elegans and is Linked to Senescence in Vascular Endothelium
These findings establish BCAP31 and POLR1E as evolutionarily conserved components of a CD44‐associated network that protects against cellular senescence and organismal aging, highlighting new potential targets for mitigating age‐related vascular decline.
Mengyu Li, Zhen-Yuan Guo, Yu-Wei Jiang et al.
· Advances in Biology · 0 citations