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Meng-Yan Li

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Open access Oct 2026

Database-Pipeline Interactions Shape Taxonomic Inference in 16S rRNA Bacterial Community Profiling

High-throughput sequencing has transformed microbiome study by enabling cost-efficient, high-resolution profiling of microbial communities using 16S rRNA gene amplicons. Despite its widespread adoption, taxonomic inference remains highly dependent on the choice of reference database and bioinformatic pipeline. To pro...

Chao Li, Liang Zhu, Lisa Axe et al. · 0 citations
Open access Sep 2026

Bifurcated Fluorotelomer Carboxylic Acid Biotransformation: Enoyl-Hydration versus Hydroxylation Regulated by Redox Conditions

Fluorotelomer carboxylic acids (FTCAs) are important precursors of perfluoroalkyl carboxylic acids (PFCAs) in wastewater and biosolids, yet their redox-dependent biotransformation remains poorly understood. We investigated 5:3 FTCA biotransformation in microcosms inoculated with activated sludge and anaerobic digester...

Bo-Yuan Su, Hao Chen, John W. Washington et al. · 0 citations
Open access Jul 2026

Computational Characterization of Ligand Recognition and Inhibition in a 1,4-Dioxane-Degrading Propane Monooxygenase

It is demonstrated that the AlphaFold-guided free energy calculations can capture experimentally observed substrate and inhibitor trends in PH-06 PRM, while identifying a remote ligand-binding pocket that warrants further mechanistic investigation.

Yishai Gilron, Jose Manuel Diaz Antunes, Devi Kumari Dhakal Gaudel et al. · 0 citations

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