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Author

Meng-Wei Wu

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2 papers indexed here

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Open access Oct 2026

Tangeretin Targets Macrophage M1 Polarization to Alleviate Liver Injury in a Murine Model of Hepatic Sinusoidal Obstruction Syndrome.

Hepatic sinusoidal obstruction syndrome (HSOS) is a life-threatening liver microvascular disorder characterized by hepatic sinusoidal endothelial cells (HSECs) injury, for which safe and effective pharmacological treatments are currently lacking. Tangeretin (TAN), a natural polymethoxylated flavone, exhibits anti-infla...

Fu-Min Zhang, Cheng Zhu, Xing-Yu Li et al. · 0 citations
Aug 2026

GDF15 ameliorates inflammatory arthritis-associated bone destruction and pain through inhibition of osteoclastogenesis and modulation of osteoclast-derived Netrin-1/CGRP+ nerve remodeling.

Findings identify GDF15 as an endogenous protective factor in inflammatory arthritis that limits osteoclastogenesis, bone destruction, and pain-related nerve remodeling, highlighting its potential as a therapeutic target for RA.

Li-Juan Mao, Hao-Ran Huang, Zhen Shao et al. · 0 citations

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