Meng-Wei Chen

Post-translational modification crosstalk in acute pancreatitis: linking acinar stress to innate immune amplification and tissue repair

Acute pancreatitis (AP) is a sterile inflammatory disease initiated by acinar cell stress and amplified through innate immune, vascular, and inter-organ responses, yet effective disease-modifying therapies remain unavailable. Although premature digestive enzyme activation, organelle stress, sterile inflammation, and mi...