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Author

Mengkun Li

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Open access Oct 2026

Antibacterial efficacy and mechanism of action of VTC3-knockout Saccharomyces cerevisiae against multidrug- resistant pathogenic bacteria

Multidrug-resistant (MDR) bacterial infections are a global public health crisis, and traditional antibiotic therapies are becoming increasingly ineffective. Probiotics represent a promising strategy in this context. In this study, we examined the antibacterial activity and mechanism of action of Saccharo...

Wei-Bao Yang, Meng-Kun Li, Yu Zhang et al. · 0 citations
Aug 2026

Acid-Mediated Antimicrobial Activity and Probiotic Potential of an SKS1-knockout Saccharomyces Cerevisiae Strain.

The SKS1-KO Saccharomyces cerevisiae showed effective antibacterial activity against common clinical pathogenic bacteria in vitro, which has been confirmed through the determination of the minimum inhibitory concentration (MIC), growth curve analysis, inhibitory spectrum analysis and co-culture experiments.

Jinyue Wang, Shulei Ji, Mengkun Li et al. · 0 citations

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