Author

Mengjia Zhang

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Open access Sep 2026

Epigallocatechin gallate (EGCG) inhibits African swine fever virus replication by targeting key viral proteins and regulating host lipid metabolism

ABSTRACT African swine fever (ASF) is a highly pathogenic swine infectious disease caused by African swine fever virus (ASFV), with a mortality rate approaching 100% in domestic pigs and causing severe economic losses to the global pig industry. Despite the recent approval of live-attenuated ASF vaccines in limited reg...

Xing-Lin He, Hong Li, Rui-Qing Yang et al. · Emerging Microbes and Infect... · 0 citations

Open access Sep 2026

Transcriptional architecture of African swine fever virus

African swine fever virus (ASFV), a large double-stranded DNA virus, poses one of the most significant infectious disease threats to the global swine industry. ASFV transcription is particularly complex because of its unique host-independent transcription system. Using nanopore sequencing technology, we accurately iden...

Gui-Qian Wang, Peng-Fei Li, Xing-Lin He et al. · PLoS Pathogens · 0 citations

Open access Aug 2026

Monoclonal antibodies target conserved S1B epitopes across deltacoronaviruses to inhibit porcine deltacoronavirus infection

ABSTRACT Porcine deltacoronavirus (PDCoV) is an emerging enteric pathogen that causes severe diarrhea, vomiting, and dehydration in piglets, and a recent human infection report raises concerns about its zoonotic potential. The S1 subunit of the PDCoV-spike protein is the primary target of neutralizing antibodies and is...

Jia-Ru Zhou, Ran Jing, Meng-Di Zhang et al. · mBio · 0 citations