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Meng-Hui Li

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Review Open access Oct 2026

SIRT2 in metabolism, aging, and longevity

SIRT2, an NAD+-dependent deacetylase, is increasingly recognized as an important regulator of cellular metabolism and aging. By deacetylating diverse substrates, SIRT2 influences glucose metabolism, lipid metabolism, mitochondrial function, cytoskeletal dynamics, oxidative stress, and inflammatory responses, thereby co...

Meng-Hui Li, Yi-Huan Dong, Wen Ren et al. · 0 citations

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