Author

Meng-Chieh Yang

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Open access Oct 2026

Metabolomic and lipidomic analyses reveal phosphatidylcholine-lysophosphatidylcholine axis alterations in sorafenib-persistent hepatocellular carcinoma.

Metabolic reprogramming and lipid remodeling are increasingly recognized as key processes underlying carcinogenesis and cancer treatment failure. The liver, as a central hub for lipid metabolism and homeostasis, is particularly susceptible to such alterations. Accordingly, hepatocellular carcinoma (HCC) exhibits extens...

Meng-Chieh Yang, Nichawadee Sandech, Sucheewin Krobthong et al. · Biomedicine & pharmacotherap... · 0 citations

#protein folding Open access Oct 2026

Coumarin–Ferulic Acid Hybrid Mediates HT-29-Selective Growth Inhibition and Proteomic Profiling

Coumarin-based molecular hybrids provide a framework for examining how structural changes influence cellular responses. This study compared four hybrids and three reference compounds across ten human cancer cell lines, with the lead hybrid also tested in non-cancerous Beas-2B cells, followed by functional assays and qu...

Sucheewin Krobthong, Meng-Chieh Yang, Pattarawit Rukthong et al. · Molecules · 0 citations