Author

Melissa C. Srougi

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Open access Sep 2026

A Research-Integrated Curriculum on CAR-T Cell Therapy

Chimeric antigen receptor (CAR) T cells are patient-derived T cells engineered to recognize specific antigens on malignant cells, representing a major breakthrough in personalized cancer immunotherapy. While CAR-T cell therapy is an established treatment for relapsed or refractory hematologic malignancies, understandin...

Youan H. Khan, Lauren Rice, Melissa C. Srougi · bioRxiv · 0 citations

2026

Open-Sourced In Silico Drug Screening.

This chapter describes a structure-based computational approach to perform high-throughput ligand screens of chemical libraries using open-source software programs and illustrates this workflow with the enzymatic molecular target NAD(P)H:quinone oxidoreductase1 (NQO1), which is overexpressed in a number of human solid...

Audrey G. Fikes, Melissa C. Srougi · Methods in molecular biology · 0 citations