JNJ-42153605, a mGluR2 PAM, potentiates Levetiracetam treatments of TBI to mitigate subsequent tau aggregation in a larval zebrafish model
LEV and JNJ-42153605 applied briefly after TBI offer a potent polypharmacy approach, at least in the preclinical animal model, to tackle the later tau aggregation and neurodegeneration that follows from TBI neurotrauma.
Laszlo F. Locskai, Shayleen Ghassemi, S. A. Tan et al.
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