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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Mei Yang

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Open access Jul 2026

Foxs1-mediated transformation of CD34+ fibroblast to myCAFs promotes tumor growth

A novel antitumor strategy that targets CAF lineage development to restrain tumor progression is proposed, and dual-recombinase lineage tracing combined with diphtheria toxin ablation demonstrates that CD34⁺Pi16⁺ cells are an essential source of tumor myofibroblasts required for tumor growth.

Junyao Yang, Ting Chen, Run Zhang et al. · 1 citation

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