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Mei-Lin Jiang

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Open access Sep 2026

Mycn facilitates hematopoietic stem and progenitor cell generation from endothelial cells by inhibiting adhesion signaling.

It is demonstrated that endothelial-specific deletion of Mycn, but not Myc, impairs HSPC formation in mouse embryos and uncovers a regulatory mechanism whereby Mycn promotes HSPC generation from endothelial cells by suppressing adhesion signaling.

Chi Wang, Zhe Chen, Mei-Lin Jiang et al. · 0 citations

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