MDV-like endogenous viral elements act as immune rheostats in Aedes cells by modulating defensin A-mediated responses to arboviruses
This study systematically characterized endogenous mosquito densovirus-like elements within the Aedes aegypti Aag2 cell line and found that these endogenous EMLs are transcriptionally active but translationally defective, highlighting a previously unrecognized role of densovirus-derived EVEs in mosquito innate immunity...