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One-third of genetically confirmed monogenic lupus patients remained unclassified, particularly those with interferon-related and nucleic acid metabolism defects, highlighting pathway-dependent limitations of current classification criteria.
BACKGROUND Large language models are increasingly used to obtain medical information, but their performance in juvenile systemic lupus erythematosus remains insufficiently characterized. OBJECTIVE To compare expert-rated response quality and clinical relevance across 4 artificial intelligence (AI) models using standa...
Comparisons of the clinical characteristics of enthesitis/ spondylitis-related juvenile idiopathic arthritis in Türkiye and India suggest that factors beyond HLA-B27, including broader genetic, environmental, and population-specific influences, may contribute to differences in disease expression.
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