Open access
Sep 2026
IL-15 signaling during a critical NK cell developmental window subverts maturation and KIR acquisition.
Natural killer (NK) cells are key mediators of immune surveillance following hematopoietic stem cell transplantation (HSCT). However, despite the post-conditioning spike in interleukin-15 (IL-15), NK cell maturation is frequently delayed following HSCT. Here, we show that during in vitro NK cell development from CD34+...
Michael A. Ruesch, Noah T. Koenigs, E. Troy et al.
· Cell Reports · 0 citations