Author

Meeqaat H. Altrufi

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Open access Aug 2026

Topical febuxostat attenuates imiquimod-induced psoriasiform dermatitis and modulates NFE2L2 (NRF2)/NLRP3 mRNA expression

Topical febuxostat demonstrated significant antipsoriatic effects in the imiquimod-induced mouse model of psoriasiform dermatitis, accompanied by improvements in oxidative stress, inflammatory cytokines, and histopathological abnormalities, which support further investigation of topical febuxostat as a potential nonste...

H. T. Alamir, W. Albahadly, H. F. Al-zubaidy et al. · Pharmacia · 0 citations

Open access Aug 2026

Nicotinamide Riboside Attenuates Cisplatin-Induced Hepatorenal Toxicity Through Restoration of NAD+ Homeostasis and Nrf2/NQO1-Dependent Antioxidant Signaling

Nicotinamide riboside exerts protective effects against cisplatin-induced hepatorenal toxicity that are mechanistically linked to activation of the Nrf2/NQO1 antioxidant pathway and restoration of hepatic NAD+ homeostasis.

W. Albahadly, M. Rasool, H. Al-Saedi et al. · Cells · 0 citations