Author

Md Solayman

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Open access Oct 2026

Lineage-specific innovations expand mitochondrial proteomes in kinetoplastids.

Trypanosoma brucei and Leishmania tarentolae are model kinetoplastids whose mitochondria contain a unique DNA network, kinetoplast DNA (kDNA), and exhibit specialized features, including developmental remodeling and RNA editing. By integrating mass spectrometry-based protein correlation profiling with published dataset...

Andres F. Vacas, Md Solayman, Sarah E. Calvo et al. · Molecules and Cells · 4 citations

Open access Oct 2026

Conserved and divergent mitochondrial assemblies in kinetoplastid parasites

SUMMARY The mitochondrial proteomes of Leishmania tarentolae and Trypanosoma brucei contain ~1,700 proteins, most of which lack homologs in higher eukaryotes. Here, we integrate complexome profiling and cryo-electron microscopy to define conserved and lineage-specific macromolecular assemblies that support mitochondria...

Md Solayman, Yi-Ting Liao, Sarah E. Calvo et al. · Molecules and Cells · 2 citations