Conformation-Selective Binding Domains of Intramolecular Chemically Induced Protein Dimerisation Systems.
It is demonstrated that CID systems can be used as building blocks for higher-order ligand-controlled protein systems and established a generalisable strategy for harnessing the affinity gains of intramolecular CID systems to create gain-of-signal assays for small molecules and ions.
Zhen-Ling Cui, Zhong Guo, Y. Liew et al.
· Angewandte Chemie · 0 citations