Open access
Sep 2026
Bcl-xL Promotes Gastric Tumorigenesis via Apoptosis-Independent Wnt/β-Catenin Activation and PPARγ Suppression.
BACKGROUND AND AIMS The Wnt/β-catenin and YAP pathways cooperatively drive gastrointestinal tumor progression. BCL2L1, a YAP target gene, encodes the anti-apoptotic isoform Bcl-xL, which is highly expressed in multiple cancers, but its role in gastric cancer remains unclear. METHODS We generated Mist1-CreERT; Apcflox...
Y. Oya, J. Arai, Yoku Hayakawa et al.
· Cellular and Molecular Gastr... · 0 citations