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Author

Mayilaadumveettil Nishana

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Open access Aug 2026

Expression quantitative trait methylation across multiple cancer types with functional and therapeutic characterization using Onco-eQTM

Abstract DNA methylation plays a crucial role in gene expression and tumorigenesis. Most pan-cancer resources primarily focus on genetic variants and their association with gene expression without clearly demonstrating how methylation itself regulates gene activity and clinical features. To address this gap, we develop...

Bhanu Teja Korra, Mayilaadumveettil Nishana, Rahul Kumar · 0 citations
2026

ChIPmentation-based mapping of histone modifications in aging: Experimental design and analytical considerations.

This chapter outlines the principles and experimental workflow of ChIPmentation, including crosslinking, chromatin fragmentation, immunoprecipitation, tagmentation, library preparation, sequencing, and data analysis, and discusses computational strategies for processing and analyzing ChIPmentation data.

Amalanandan Johna, Sreedarsanam Sreya, Sengupta Tiyas et al. · 0 citations

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