Copper Shapes T Cell Metabolism and Epigenetics to Drive Pathogenic Th17 Cell Function in Autoimmunity 2259915
Pathogenic T helper 17 (pTh17) cells are a subset of CD4+ T cells driving autoimmune diseases including multiple sclerosis (MS). To identify transporters controlling pTh17 cells, we conducted an in vivo shRNA-based forward genetic screen using the experimental autoimmune encephalomyelitis (EAE) model of MS...