Integrative structural modelling reveals the human Mic60-Mic19 subcomplex as a diffusion barrier in mitochondria
Mitochondrial crista junctions (CJs) operate as regulated gateways into the cristae microenvironment, whose protein, metabolite, and ion compositions are finely tuned for mitochondrial function. The Mic60-Mic19 complex of the mitochondrial contact site and cristae organizing system (MICOS) complex was suggested to span...
Evangelia Nathanail, Edoardo Rolando, Max Ruwolt et al.
· Nature Communications · 0 citations