Mavee S. Witherspoon

Noncanonical role for Caspase-5 in the human intestinal epithelium 2267092

Caspase-5 (CASP5) is a member of the inflammatory caspase family of cysteine proteases involved in inflammation and cell death. CASP5 shares highest homology with inflammatory caspase-4, but while caspase-4 is essential for noncanonical inflammasome activation, CASP5 is generally dispensable. This conundrum has l...