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Author

Maurizio Fanciulli

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2 papers indexed here

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Review Open access Oct 2026

Towards epigenetically informed and biobank-driven precision immunotherapy in melanoma

Cutaneous melanoma (CM) is a highly immunogenic and therapeutically intricate solid tumor, exemplifying the interactions between tumors and the immune system. Despite the significant enhancement in survival rates for patients with advanced melanoma due to immune checkpoint inhibitors (ICIs), numerous patients either ex...

L. Ciuffreda, I. Falcone, C. Sorino et al. · 0 citations
Open access Sep 2026

KDM6A loss enhances oxidative phosphorylation uncovering tissue-level convergent evolution

The tumor suppressor KDM6A/UTX, a histone demethylase and a 2-oxoglutarate-dependent dioxygenase, is frequently lost in many cancer types. We show that KDM6A loss pervasively activates oxidative phosphorylation in several solid tumors, generating a pseudo-hyperoxic environment, opposite from the pseudo-hypoxia observed...

Antonino Alex Cartalemi, D. Rosano, Camilla Ferrari et al. · 0 citations

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