Author

Matthias M. Herth

2 papers indexed here

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Open access Oct 2026

Click-to-Release Reactivity of Quaternary Anilinium Tetrazines Enables Cascade Assembly of Multifunctional Biomolecular Scaffolds.

Click chemistry has evolved from its origins in forming covalent connections to also include breaking bonds, cleaving linkers, and liberating cargo, creating broad applications in chemical biology and biomedicine. The reaction sequences that drive these tools are complex, and thus prone to an array of dead-end intermed...

Markus Staudt, C. Poulie, A. Löffler et al. · Angewandte Chemie · 0 citations

Open access Aug 2026

Preclinical evaluation of homodimeric FAPI target modules for UniCAR-mediated targeting of FAP-expressing tumor and stromal cells

Abstract Due to its overexpression in the tumor microenvironment of most solid malignancies, fibroblast activation protein (FAP) has emerged as an ideal target for (immuno)theranostic applications. The clinically tested UniCAR system represents a promising adapter CAR T-cell approach, in which CAR T-cell activity is re...

Hugo Boutier, Simona Mattiussi, L. Loureiro et al. · Oncoimmunology · 1 citation