Author

Matthew S. Kayser

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Open access Sep 2026

Sensory-sleep dysfunction is a shared phenotype across genetically distinct neurodevelopmental disorder models

Sensory abnormalities and sleep disruption frequently co-occur in neurodevelopmental disorders (NDDs), but how sensory input interacts with sleep regulation in NDDs remains poorly understood. Here, we examined vibration-induced sleep (VIS), in which prolonged gentle vibration promotes sleep in Drosophila, in three gene...

Jadwiga N. Bilchak, Kyla Mace, J. Luong et al. · bioRxiv · 0 citations

Open access Sep 2026

The evolutionarily conserved EHMT1/G9a histone methyltransferase family regulates sleep maintenance through ROS homeostasis in insulin-producing cells

It is shown that G9a is required in insulin-producing cells (IPCs) and the fat body, in the latter during development, to ensure adult sleep integrity, and that a Drosophila sleep-restriction paradigm based on human sleep-restriction therapy can override the developmental defects and restore sleep continuity in adultho...

Mireia Coll-Tané, Lara V. van Renssen, Nicholas Raun et al. · bioRxiv · 0 citations