Author

Matthew D. Woolard

2 papers indexed here

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Open access Sep 2026

RIPK3 acts as a molecular switch between neuroprotection and neuropathology during herpes simplex encephalitis

Herpes simplex virus type 1 (HSV-1) is the leading cause of sporadic viral encephalitis, where uncontrolled viral replication and neuroinflammation drive fatal brain injury. Inherited RIPK3 deficiency predisposes humans to severe disease, but the protective mechanism remains unclear. Using single-cell transcriptomics,...

Shu-Qi Wang, Jian Wang, Madison Hicks et al. · Nature Communications · 0 citations

Jul 2026

Lipin-1 promotes mitochondrial respiration to facilitate macrophage pro-resolving responses 2253765

The findings show that lipin-1 aids MERCs formation and cardiolipin synthesis to support macrophage efferocytosis and pro-resolving responses, which deepens the insight into the cellular and molecular mechanisms driving inflammation resolution and atherosclerosis regression.

Oluwakemi O. Igiehon, Temitayo T. Bamgbose, Robert M. Schilke et al. · Journal of Immunology · 0 citations