Author

Matteo Pellegrini

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Open access Oct 2026

Is epigenetics Lamarck’s revenge? The evolutionary and ecological impacts of DNA methylation in a California oak

Epigenetics has been proposed as a basis for Lamarckian inheritance of acquired characteristics. This hypothesis raises questions about environmental induction of DNA methylation, its persistence across generations, and associations with gene expression. We investigated these processes in the California oak, Quercus lo...

V. Sork, Lily D. Peck, Luke Browne et al. · bioRxiv · 0 citations

Open access Aug 2026

Physics-Informed Modeling of Biological Aging through DNA Methylation Entropy

An information-theoretic framework for DNA methylation dynamics combined with nonlinear machine learning is introduced to develop a competitive and interpretable age predictor and the Stacy Gradient Boosting Clock (Stacy-GB), which combines this GGD-based representation with a LightGBM regressor.

Hosein Nasrolahpour, Ales Jandera, T. Škovránek et al. · bioRxiv · 0 citations