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Matlock A. Jeffries

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Review Open access Sep 2026

What does the gut microbiome teach us about osteoarthritis development and progression?

Osteoarthritis is a degenerative disorder of the whole joint and the leading cause of chronic disability in older adults, yet no disease-modifying therapy exists. Here we review what the gut microbiome teaches us about how osteoarthritis develops and progresses. We outline a biologically plausible gut-joint axis in whi...

G. Dyson, C. Brawner, Matlock A. Jeffries · 0 citations

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