Open access
Sep 2026
Hypertrophic cardiomyopathy: a genome-wide association meta-analysis and polygenic risk score.
BACKGROUND Hypertrophic cardiomyopathy (HCM) is a heritable trait with marked variability in expression and outcomes. Our aims were to discover new genetic loci associated with HCM and to test the effect of a new polygenic risk score (PRS) on incidence, phenotype and outcomes stratified by genotype status. METHODS A...
Luis R. Lopes, Nay Aung, S. van Duijvenboden et al.
· Journal of Medical Genetics · 0 citations