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Masaomi Motegi

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Open access Aug 2026

Myofibroblast‐Like CAFs in Metastatic Lymph Nodes Drive Tumor Stemness and Poor Prognosis in Head and Neck Cancer

ABSTRACT Lymph node (LN) metastasis is one of the major prognostic factors in head and neck squamous cell carcinoma (HNSCC), and treatment sensitivity often differs between primary tumors and metastatic LNs. Beyond tumor cell–intrinsic differences, heterogeneity of the tumor microenvironment may contribute to these dis...

Hiroyuki Hagiwara, Hideyuki Takahashi, Reika Kawabata-Iwakawa et al. · 0 citations

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