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Author

Masamitsu N. Asaka

2 papers indexed here

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Open access Sep 2026

A novel recombinant BCG vaccine using a mycobacteriophage promoter shows improved protection against tuberculosis

The limited efficacy of conventional bacillus Calmette–Guérin (BCG) vaccination against adult pulmonary tuberculosis highlights the need for improved vaccine strategies. Genome integration can overcome the plasmid instability of recombinant BCG, but we hypothesized that this approach would be constrained by reduced tra...

Y. Tsukamoto, Yusuke Tsujimura, Tetsu Mukai et al. · 0 citations
Open access Oct 2026

Long-term immunoprophylaxis by TLR9 ligand mediates macrophage-ILC cross-talk against respiratory viral infection

Rapid development of host immunity is critical during the emergence of viral outbreaks when vaccines are not yet available. Here, we demonstrate that CpG oligodeoxynucleotide-schizophyllan complex (K3-SPG) induces antigen-independent, long-term protection against lethal respiratory virus infection. A single intranasal...

Asuka Joy Tobuse, K. Kobiyama, Jun Tsuchida et al. · 0 citations

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