Masahiro Horizoe

Excess glutamine in embryo culture media alters mitochondrial and autophagy-related dynamics associated with impaired postnatal development

The preimplantation period is a critical nutrient-sensing window influencing metabolic disease risk, as established by the developmental origins of health and disease theory (DOHaD). In this study, we examined the postnatal consequences of increased glutamine concentration, an important energy source, by altering embry...